作者： C. Ma^a;X.W. Yang^a;Y.H. Li^b;J.Z. Yu^b;C.Y. Liu^b;J.J. Huang^c;J.C. Liu^a;W.J. Jiang^a;Q.J. Feng^a;B.G. Xiao^d （a “2011” Collaborative Innovation Center/Research Center of Neurobiology, Shanxi University of Traditional Chinese Medicine, Taiyuan, Chinab Institute of Brain Science, Shanxi Datong University, Datong, Chinac Department of Neurosurgery First Hospital, Datong Coalmine Group, Datong, Chinad Institute of Neurology Huashan Hospital Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China）

出处： Journal of the Neurological Sciences 2015 Vol.357 Suppl 1 Pe2

作者： C. Ma^a;P.J. Zhang^b;M.F. Guo^b;Y.X. Xing^b;D.B. Yang^b;L.H. Zhang^b;Y.H. Li^b;H.F. Zhang^c;H.Z. Zhang^a;H.Q. Xue^a;Q.J. Feng^a;B.G. Xiao^d （a “2011” Collaborative Innovation Center/Research Center of Neurobiology, Shanxi University of Traditional Chinese Medicine, Taiyuan, Chinab Institute of Brain Science, Shanxi Datong University, Datong, Chinac Department of Neurology, The Fifth People's Hospital of Datong, Shanxi, Chinad Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China）

出处： Journal of the Neurological Sciences 2015 Vol.357 Suppl 1 Pe16

作者： Guo A;Zhang S;Wang K;Zhu R. （1School of Chinese Materia Medica, Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, People's Republic of China.2Department of Chemistry, Taiyuan Normal University, Taiyuan 030031, People's Republic of China.）

出处： Acta Crystallogr E Crystallogr Commun 2015 Vol.71 Part 9 Po686-o687

关键词： 2-hy­droxy-1-naphthaldehyde;N—H⋯O hydrogen bonding;O—H⋯O hydrogen bonding;Schiff base;crystal structure

摘要： The title compound, C15H17NO4, containing two mol-ecules in the asymmetric unit is a polymorph of the crystal structure published by Martínez et al. [ ...

作者： Fengmei Lian;Jiaxing Tian;Xinyan Chen;Zhibin Li;Chunli Piao;Junjie Guo;Licheng Ma;Lijuan Zhao;Chengdong Xia;Chong-Zhi Wang;Chun-Su Yuan ;Xiaolin Tong （Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China ; Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China ; Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China ; Shijiazhuang Hospital of Traditional Chinese Medicine, Shijiazhuang, China ; The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China ; Shanxi Province Hospital of Traditional Chinese Medicine, Taiyuan, China ; Bethune International Peace Hospital, Shijiazhuang, China ; The Affiliated Hospital to Shanxi University of Traditional Chinese Medicine, Taiyuan, China ; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China ; Tang Center for Herbal Medicine Research, University of Chicago, Chicago, IL, United States of America ; Tang Center for Herbal Medicine Research, University of Chicago, Chicago, IL, United States of America ; Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China）

出处： PLOS ONE 2015 Vol.10 No.6 Pe0130550

摘要： Metformin plays an important role in diabetes treatment. Studies have shown that the combined use of oral hypoglycemic medications is more effective t ...

作者： Zhao Zhang;Yun Zhang;Zheng Mou;Shifeng Chu;Xiaoyu Chen;Wenbin He;Xiaofeng Guo;Yuhe Yuan;Masami Takahashi ;Naihong Chen （State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China, Basic Medical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, People’s Republic of China ; Basic Medical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, People’s Republic of China ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China ; Department of Biochemistry, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Department of Pharmacology, Institute of Materia Medica, and neuroscience center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China）

出处： PLOS ONE 2014 Vol.9 No.4 Pe94574

摘要： Protein tyrosine kinases, which are highly expressed in the central nervous system, are implicated in many neural processes. However, the relationship ...

作者： Guo, AL;Zhang, SR;Liu, XF;Jiao, JH （aDepartment of Traditional Chinese Pharmacology, Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, People's Republic of China）

出处： Acta crystallographica. Section E: Structure reports online 2011 Vol.67 PO285-U2086

摘要： The title compound, C(19)H(17)NO(2), represents a trans isomer with respect to the C=N bond. The dihedral angle between the planes of the naphthyl rin ...

作者： Tao Yang¹;Niping Qin²;Fahui Liu³;Yihan Zhao⁴;Wanning Liu⁵;Daiming Fan¹CA1 （¹State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China;²The First Clinical Medical College, Shanxi Medical University, Taiyuan 030600, China;³Xiamen Cell Therapy Research Center, The First Affiliated Hospital of Xiamen University, Xiamen University, Xiamen 361003, China;⁴Second Clinical College, Shanxi University of Traditional Chinese Medicine, Xi'an 712046,China;⁵College of Life Sciences, Northwest University, Xi'an 710069, China）

出处： Life Sciences 2024

关键词： Berberine;Interstitial microbiome;Metabolism homeostasis;Ulcerative colitis.

摘要： Aims This study aims to investigate the effects of berberine (BBR) on the intestinal microbiome (IM) and serum metabolome in ulcerative colitis (UC). ...

作者： Hou, Yi Wen^a;Liu, Ying^a;Li, Zhu Rong^a;Chen, Chen^a;Li, Zhen Cheng^a;Liu, Yang^a （^aSchool of Basic Medical Sciences, Shanxi University of Chinese Medicine, Shanxi Province, Jinzhong, 030619, China）

出处： Chinese Journal of Tissue Engineering Research 2024

关键词： autoimmune hepatitis;circular RNAs (CircRNAs);concanavalin A;correlation analysis;liver injury

摘要： BACKGROUND: The pathogenesis of autoimmune hepatitis has not been clearly elucidated. Circular RNA (CircRNA) is a research hotspot in the field of RNA ...

作者： Haixia Ji¹CA1;Wenzhe Wang²;Ou Qiao²;Xuliang Hao³CA2 （¹School of Chemical Engineering and Technology, North University of China, Taiyuan 030012, P.R. China;²School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, P.R. China;³Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan 030012, P.R. China）

出处： ACS Applied Nano Materials 2024

关键词： nanodrugs;carrier-free;supramolecular self-assembly;anticancer drugs;the driving force

摘要： Nanodrugs represent a drug delivery form that brings hope for optimal drug release due to their inherent properties. Special carrier materials give hy ...

作者： Yuting Gao¹;Yi Gong¹;Junlan Lu¹;Huiqin Hao²;Huiqin Hao³;Xinli Shi¹ （¹Laboratory of Integrated Medicine Tumor Immunology, Shanxi University of Chinese Medicine, Taiyuan, China;²Chinese Medicine Gene Expression Regulation Laboratory, State Administration of Traditional Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, China;³Basic Laboratory of Integrated Traditional Chinese and Western, Shanxi University of Chinese Medicine, Taiyuan, China）

出处： Frontiers in Immunology 2024

关键词： YAP1;liver cancer;immune checkpoint inhibitors;tumor microenvironment;metabolic reprogramming

摘要： Liver cancer is the third leading of tumor death, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). Immune checkpoin ...