作者： Jun-Jun Yin;Yan He;Jun An;Qiang Miao;Ruo-Xuan Sui;Qing Wang;Jie-Zhong Yu;Bao-Guo Xiao;Cun-Gen Ma;Cun-Gen Ma （The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China Shanxi Key Laboratory of Inflammatory Neurodegenerative Diseases, Institute of Brain Science, Shanxi Datong University, Datong, China Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China Shanxi Key Laboratory of Inflammatory Neurodegenerative Diseases, Institute of Brain Science, Shanxi Datong University, Datong, China）

出处： Frontiers in Cellular Neuroscience 2020

关键词： Ginkgolide B;cuprizone-induced demyelination;microglia;astrocytes;remyelination

摘要： Multiple sclerosis (MS) is an inflammatory demyelinating disorder in the central nervous system (CNS), in which remyelination failure results in persi ...

作者： Sha-Sha Wang;Hao-Zhi Bi;Shi-Feng Chu;Yi-Xiao Dong;Wen-Bin He;Ya-Juan Tian;Ying-Da Zang;Dong-Ming Zhang;Zhao Zhang;Nai-Hong Chen （Institute of Pharmaceutical &Food Engineering, Shanxi University of Traditional Chinese Medicine, Taiyuan, 030619, China;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica &Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica &Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Institute of Pharmaceutical &Food Engineering, Shanxi University of Traditional Chinese Medicine, Taiyuan, 030619, China. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica &Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Electronic address: zhangzhao@imm.ac.cn. Institute of Pharmaceutical &Food Engineering, Shanxi University of Traditional Chinese Medicine, Taiyuan, 030619, China;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica &Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China;Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: chennh@imm.ac.cn.）

出处： Brain research bulletin 2020

关键词： CZ-7 Cuprizone Demyelinating disease Microglia Myelin debris Remyelination

摘要： The mechanism of demyelinating diseases is controversial, while demyelination and remyeliantion disorder is the acknowledged etiology and therapeutic ...

作者： Yang Liu;Yuting Gao;Huiqin Hao;Tiezheng Hou （Department of Pathology, College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619 China;Department of Pathology, College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619 China;Department of Pathology, College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619 China;T. Hou and H. Hao, Department of Pathology, College of Basic Medical Sciences, Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China;Department of Pathology, College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619 China;T. Hou and H. Hao, Department of Pathology, College of Basic Medical Sciences, Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China）

出处： FEBS Open Bio 2020

关键词： immune check point and T cell survival;macrophage;PD‐1 (CD279);PDL‐1 (CD273) and PDL‐2 (CD274);Treg

摘要： CD279 is a cell surface protein predominantly expressed on T cells. Its ligands CD273 and CD274 are expressed on antigen‐presenting cells and tumors. ...

作者： Yi Hui  ¹ , Shu-Guang Yan  ¹ , Qian Wang  ¹ , Jing-Tao Li  ² , Hai-Liang Wei  ² , Yu-Peng Shan  ³ （Affiliations 1 Shanxi University of Chinese Medicine, Xianyang 712046. 2 The Hospital Afiliated to Shanxi University of Chinese Medicine, Xianyang 712000. 3 Department of Oncology Tangdu Hospital, Air Force Military Medical University, Xian 710038, China.）

出处： Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 2020

摘要： Objective: To observe the regulatory effect of 6-Shogaol on Notch signal pathway in colonic epithelial cells of mice with ulcerative colitis. Methods: ...

作者： Xianglong Meng  ^{1   2} , Junnan Ma  ¹ , An Na Kang  ¹ , Seok Yong Kang  ^{1   3} , Hyo Won Jung  ^{1   3} , Yong-Ki Park  ^{1   3} （Affiliations 1 Department of Herbology, College of Korean Medicine, Dongguk University, Gyeongju, South Korea. 2 Experimental Teaching Center, College of Chinese Materia Medica and Food Engineering, Shanxi University of Chinese Medicine, Jinzhong, China. 3 Korean Medicine R&D Center, Dongguk University, Gyeongju, South Korea.）

出处： Frontiers in pharmacology 2020

关键词： Bekhogainsam decoction;diabetic nephropathy;gut microbiota;metabolomics;network pharmacology.

摘要： Bekhogainsam decoction (BHID), a representative prescription for the treatment of diabetes mellitus (DM) and diabetic complications in both traditiona ...

作者： Xiao-Jun Gou;Huan-Huan Bai;Li-Wei Liu;Hong-Yu Chen;Qi Shi;Li-Sheng Chang;Ming-Ming Ding;Qin Shi;Mei-Xiang Zhou;Wen-Li Chen;Li-Min Zhang （Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine of Shanghai, Shanghai 201999, China. School of Pharmacy, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China. School of Basic Sciences of Shanxi University of Chinese Medicine, Taiyuan, China.）

出处： BioMed research international 2020

摘要： Objective: To explore the ability of asiatic acid to interfere with the invasion and proliferation of breast cancer cells by inhibiting WAVE3 expressi ...

作者： Yu-Xuan Wang  ¹ , Hai-Ying Liu  ² , Jin-Hong Ren  ¹ , Hua-Feng Zhang  ² , Hui-Qing Xue  ¹ （Affiliations 1 Shanxi Key Laboratory of Innovative Drug for the Treatment of Serious Diseases Basing on the Chronic Inflammation, Shanxi University of Traditional Chinese Medicine Jinzhong 030619, China. 2 Academy of Life Science, University of Science and Technology of China Hefei 230031, China.）

出处： Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2020

关键词： Halenia elliptica;RNA-seq;autophagy;traditional Chinese medicine ingredient;xanthone.

摘要： To investigate the inhibitory effects of two xanthone compounds, 1-hydroxy-2,3,4,8-4 methoxy xanthone(here in after referred to as Fr15) and 1-hydroxy ...

作者： Yu-Lu Miao;Pan He;Wen-Xia Zhang;Wen-Zhi Zhang;Min Feng;Yan Ni （Shanxi Provincial Academy of Traditional Chinese Medicine Taiyuan 030012, China. Shanxi University of Traditional Chinese Medicine Taiyuan 030619, China.）

出处： China journal of Chinese materia medica 2020

关键词： Crepis crocea;anti-inflammation;immunoblotting;inflammatory cytokines;metabonomics

摘要： Based on ~1H-NMR metabonomics technique and Western blot assay, the anti-inflammatory mechanism of Crepis crocea was discussed. In this study, male SD ...

作者： X X Lian;Y P Sun;X X Guo （Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China. Institute of Chinese Medicine in Shanxi Province, Taiyuan 030012, China. Shanxi Hospital of Traditional Chinese Medicine, Taiyuan 030012, China.）

出处： Chinese journal of hepatology 2020

关键词： Amine oxidase (copper-containing);Endotoxins;Liver cirrhosis;Permeability

摘要： Objective: To investigate the correlation between changes in intestinal mucosal permeability and prognosis of patients with liver cirrhosis. Methods: ...

作者： Qi Liu;Jianguo Wang;Yu Guo;Lu Jia;Haijun Yuan;Wanfang Yang;Yangxuan Wen （Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, Shanxi, China. Shanxi Hospital of Integrated Traditional and Western Medicine, Taiyuan 030013, Shanxi, China. Corresponding author: Liu Qi, Email: angel200644@126.com.）

出处： Zhonghua wei zhong bing ji jiu yi xue 2020

摘要： OBJECTIVE: To analyze the differential gene expression of Shufeng Xuanfei Jiedu formula on whole expression profiles of the inflammation-related cytok ...